江华

擅长： 一直从事临床医疗工作，擅长造血干细胞移植以及儿童血液病的诊治。2008年在美国DUKE大学造血干细胞移植中心留学，在造血干细胞移植治疗儿科各种疾病和小儿血液病的诊治方面有丰富经验。贫血，白血病，多发性骨髓瘤。

简介： 中华医学会儿科分会肿瘤学组委员；中国抗癌协会小儿肿专业委员会第七届委员；广东省抗癌协会小儿肿瘤专业委员会第三届委员会常委；广东省医学会儿科学分会第十六届委员；广东省医学会血液学分会第九届委员；广东省医师协会肿瘤科医师分会第三届委员会委员；广东省医师协会血液科医师分会第二届委员会委员；广东省地中海贫血防治协会地中海贫血治疗专业委员会常委；广东省地中海贫血防治协会理事；《中国小儿血液与肿瘤》编委长期从事儿童血液肿瘤性疾病的的临床诊治及基础研究等工作，尤其在造血干细胞移植治疗儿童各类疾病（包括肿瘤性疾病和遗传性疾病、代谢性疾病、免疫缺陷性疾病等）方面，有一定造诣和影响力，先后在美国圣裘德儿童研究医院移植部临床学习和加拿大多伦大学附属总医院血液实验室从事访问研究，主持承担多项国家及地方课题，发表论文40余篇。专业专长造血干细胞移植治疗各种类型血液疾病研究领域造血干细胞移植以及其他各类儿童血液肿瘤疾病。科研成果作为负责人，承担并完成上海市教委资助项目、上海市卫生局课题以及国家自然科学基金面上项目各一项；2013年来到广州后，先后成功申请广东省自然科学基金及广东省卫计委课题各一项。近年发表文章：1.Jiang, H; Ou, Z; He, Y; Zhang, K;et al. DNA methylation markers in the diagnosis and prognosis of common leukemias. Signal Transduct Target Ther. 2020 ;5:32.Yang, X; Wu, X; Fang, N; Jiang H, Xu, L. FOXO3 gene polymorphisms influence the risk of acute lymphoblastic leukemia in Chinese children. J Cell Biochem.2020 Feb ;121(2):2019-2026（通讯作者）3.Jiang, H; Jiang, F; Li, J; Li, DZ; Congenital Nonspherocytic Hemolytic Anemia Caused by Krüppel-Like Factor 1 Gene Variants.Hemoglobin. 2019; 43 (4-5):292-2954.Jiang, H; Zhou, JY; Li, J; Li, DZ; Unstable Hemoglobin Variants: The Need for Clinical Vigilance in Infants with Congenital Jaundice. Hemoglobin.2019 Jan ;43(1):60-625.Ye Q, Jiang H, Jiang H. A comparison of the effect of xinruibai versus filgrastim on hematopoietic reconstruction after allogeneic hematopoietic stem cell transplantation. Ital J Pediatr. 2018 May 31;44(1):63. （通讯作者）6.Liu X, Peng H, Liao W, Luo A, Cai M, He J, Zhang X, Luo Z, Jiang H, Xu L.MiR-181a/b induce the growth, invasion, and metastasis of neuroblastoma cells through targeting ABI1.Mol Carcinog. 2018 May 26. 2018 Sep;57(9):1237-1250 doi: 10.1002/mc.22839. （通讯作者）7.Jiang H, Huang LY, Zhen L, Jiang F, Li DZ.Two α1-Globin Gene Point Mutations Causing Severe Hb H Disease.Hemoglobin. 2017 Jul - Nov;41(4-6):293-296. doi: 10.1080/03630269.2017.1390478. Epub 2017 Nov 8.8.Yang D, Cheng D, Tu Q, Yang H, Sun B, Yan L, Dai H, Luo J, Mao B, Cao Y, Yu X, Jiang H, Zhao X. HUWE1 controls the development of non-small cell lung cancer through down-regulation of p53. Theranostics. 2018 Jun 6;8(13):3517-3529. doi: 10.7150/thno.24401. eCollection 2018.（通讯作者）9.Liu YF, Chen YY, He YY, Wang JY, Yang JP, Zhong SL, Jiang N, Zhou P, Jiang H, Zhou J. Expansion and activation of granulocytic, myeloid-derived suppressor cells in childhood precursor B cell acute lymphoblastic leukemia. J Leukoc Biol. 2017 Aug;102(2):449-458. doi: 10.1189/jlb.5MA1116-453RR. Epub 2017 Jun 15.（通讯作者）10.Jiang H, Yan JM, Zhou JY, Li DZ. Hb Alesha [β67(E11)Val→Met (GTG>ATG); HBB: c.202G > A] Found in a Chinese Girl. Hemoglobin. 2016 Nov;40(6):420-421. 11.Liu S, Jiang H, Huang LY, Li DZ. A de novo ankyrin mutation (ANK1 Q109X) causing severe hereditary spherocytosis from preterm neonatal period. Ann Hematol. 2017 Jun;96(6):1067-1068.12.Jiang H, Liu S, Zhang YL, Wan JH, Li R, Li DZ.Association of an α-globin gene cluster duplication and heterozygous β-thalassemia in a patient with a severe thalassemia syndrome. Hemoglobin. 2015;39(2):102-6.13.Jiang H, Jiang MY, Liu S, Cai YN, Liang CL, Liu L.Combination of a Haploidentical Stem Cell Transplant With Umbilical Cord Blood for Cerebral X-Linked Adrenoleukodystrophy. Pediatric Neurology. 2015, 53(2):163-165 14.Jiang H, Wu MY, Li DZ.A Novel Mutation of Ribosomal Protein S19 Gene in a Chinese Child with Diamond-Blackfan Anemia. Indian J Hematol Blood Transfus. 2016, 32(1):233-23415.Jiang H, Yan JM, Li J, Xie XM, Li DZ. Diagnostic dilemma of hemoglobin Perth [β32(B14)Leu→Pro; HBB: c.98T > C] in Mainland China . Hemoglobin. 2016, 40(3):202-20516.Jiang H, Liu S, Zhang YL, Wan JH, Li R, Li. DZ.Association of an α-globin gene cluster duplication and heterozygous β-thalassemia in a patient with a severe thalassemia syndrome. Hemoglobin. 2015;39(2):102-617.Ye M, Wei W, Yang Z, Li Y, Cheng S, Wang K, Zhou T, Sun J, Liu S, Ni N, Jiang H, Jiang H.Rapid diagnosis of Propionibacterium acnes infection in patient with hyperpyrexia after hematopoietic stem cell transplantation by next-generation sequencing: a case report. BMC Infect Dis. 2016 Jan 8;16(1):5. (通讯作者)18.Liu S, Jiang H, Wu MY, Zhang YL, Li DZ.Thalassemia Intermedia Caused by 16p13.3 Sectional Duplication in a β-Thalassemia Heterozygous Child.Pediatr Hematol Oncol. 2015;32(5):349-53.19.Xiaodan Liu, Wang Liao, Hongxia Peng，Xuequn Luo, Ziyan Luo, Hua Jiang, Ling Xu. miR-181a promotes G1/S transition and cell proliferation in pediatric acute myeloid leukemia by targeting ATM，J Cancer Res Clin Oncol. 2015, 142(1):77-87. 20.江华，顾龙君，薛惠良，汤静燕，陈静，潘慈，陈静。ALL患儿肿瘤细胞的门冬酰胺合成酶活性研究。中国当代儿科杂志，2006，8（4）：272－421.江华，顾龙君，薛惠良，陈静，潘慈，陈静。ALL患儿诱导缓解治疗中血浆L-Asp活性及抗L-Asp抗体水平变化。中国小儿血液与肿瘤杂志，2006，12（6）：289－9222.江华，顾龙君，薛惠良，汤静燕，陈静，潘慈，陈静，徐翀，董璐，周敏。儿童非成熟B淋巴细胞性白血病预后因素分析。中国当代儿科杂志，2008，10（3）：290－29423.Saha MN, Jiang H, Mukai A, Chang H. RITA inhibits multiple myeloma cell growth through induction of p53-mediated caspase-dependent apoptosis and synergistically enhances nutlin-induced cytotoxic responses. Mol Cancer Ther. 2010 9(11):3041-51.(并列第一作者)24.Saha MN, Jiang H, Chang H. Molecular mechanisms of nutlin-induced apoptosis in multiple myeloma: evidence for p53-transcription-dependent and -independent pathways. Cancer Biol Ther. 2010;10(6):567-78.25.Chang H, Jiang N, Jiang H, Saha MN, Qi C, Xu W, Reece D. CKS1B nuclear expression is inversely correlated with p27Kip1 expression and is predictive of an adverse survival in patients with multiple myeloma. Haematologica. 2010;95(9):1542-7.26.Saha MN, Jiang H, Jayakar J, Reece D, Branch DR, Chang H. MDM2 antagonist nutlin plus proteasome inhibitor velcade combination displays a synergistic anti-myeloma activity. Cancer Biol Ther. 2010;9(11):936-44. 27.Jiang A, Jiang H, Brandwein J, Kamel-Reid S, Chang H. Prognostic factors in normal karyotype acute myeloid leukemia in the absence of the FLT3-ITD mutation. Leuk Res. 2011;35(4):492-828.罗成娟，江华，陈静，戴家乐，沈小钰，薛惠良，汤静燕，罗长缨，潘慈，沈树红，周敏，顾龙君。儿童急性淋巴细胞白血病T细胞受体重排删除环与严重感染相关性研究。 中国当代儿科杂志，2011，13（6）：466－70.（通讯作者）29.Saha MN, Jiang H, Yang Y, Zhu X, Wang X, Schimmer AD, Qiu L, Chang H. Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma. PLoS One. 2012; 7(1): e3021530.江华，,胡文婷，陈静，罗长缨，王坚敏，周敏，叶启东，汤燕静，罗成娟。异基因造血干细胞移植治疗儿童慢性粒细胞性白血病的疗效分析。中国当代儿科杂志，2013,15（1）：19-2431.王卓，梁欢欢，李本尚，黄小航，张婧，王翔，丁丽霞，江华。锌指蛋白ZFX在儿童B系急性淋巴细胞性白血病中的表达及意义。中国当代儿科杂志，2013,15（7）：509-513（通讯作者）32.江华，缪艳，陈静，罗长缨，王坚敏。异基因造血干细胞移植治疗儿童高危急性髓系白血病28例疗效分析。中国实用儿科杂志，2013,28（8）:601-60533.江华，陈静，罗长缨，王坚敏。异基因造血干细胞移植治疗儿童骨髓增生异常综合征疗效分析。中华实用儿科临床杂志，2013,28（15）：1150-115434.江华，周莺，陈静，罗长缨，王坚敏。儿童异基因造血干细胞移植导致后部可逆性脑病综合征临床分析。中华临床医师杂志（电子版），2013,7（22）：9853-985635.Saha MN, Jiang H, Yang Y, Reece D, Chang H. PRIMA-1Met/APR-246 Displays High Antitumor Activity in Multiple Myeloma By Induction of p73 and Noxa. Mol Cancer Ther. 2013，12（11）：2331-41